Zelgor 250mg
Description
Zelgor 250 mg Tablet is an anticancer drug used in men along with another drug called prednisone for the treatment of prostate cancer that has spread to other parts of the body. It is generally used in patients who are not responding to other treatment options.
Uses Of Zelgor
The patient clinically not used for chemotherapy with prednisone or prednisolone will preferred treatment with metastatic CRPC in adult men. Zelgor is an inhibitor of CYP17 which is used to treats the patients with metastatic castration-resistant prostate cancer, The patient have received earlier chemotherapy with docetaxel combination with prednisone and in failure of androgen deprivation treatment.
Dosage & Administration
• Zelgor tablets in Combination with prednisone 5 mg administered orally twice daily.
• Prescribed dose of Zelgor tablets is 1,000 mg, Zelgor 250mg given 4 dose orally once in a day (OD).
• Zelgor Tablets administrated on an empty stomach.
• No food should be consumed for at least 2 hours before and at least 1 hour after the dose of Zelgor Tablets is taken.
Drug Interaction
Drugs that inhibits or induce CYP3A4
Abiraterone interaction with strong CYP3A4inhibitors or inducers, the pharmacokinetics of Abiraterone is not evaluated properily, so avoid or use with caution while abiterone therapy.
Effects of Abiraterone on drug metabolizing enzymes
Abiraterone is a hepatic drug-metabolizing inhibitor CYP2D6, when substrates (dextromethorphan) of it is co administrated with Abiraterone will increases the Cmax and AUC dextromethorphan.
For more Information
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