Xbira 250mg
Description
Abiraterone acetate is a type of hormone therapy It.. XBIRA Abiraterone works by reducing androgen production in the body. Androgens are male hormones that can promote tumor growth in the prostate.
Usage Of Xbira
It is used to treats the patients with metastatic castration-resistant prostate cancer.
The patient clinically not used for chemotherapy with prednisone or prednisolone will preferred treatment with metastatic CRPC in adult men.Dosage & Administration
Xbira tablets in Combination with prednisone 5 mg administered orally twice daily.• Xbira Tablets administrated on an empty stomach. No food should be consumed for at least 2 hours before and at least
Mechanism Of Action
An enzyme CYP17A1 which catalyzes the biosynthesis of androgen and is highly expressed in testicular, adrenal, and prostatic tumor tissue. Particularily , abiraterone prevents the conversion of 17-hydroxyprognenolone to dehydroepiandrosterone (DHEA) by the enzyme CYP17A1 to reduce serum levels of testosterone and other androgens.
A type of steroidal enzyme inhibitor CYP17A1 (17 alpha-hydroxylase/C17,20 lyase) is known as abirateron acetate which is an orally active and It interefere with CYP17A1 in a selective and invariable manner through covalent binding mechanism.
For more Information
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