Gefitinib 250mg
Gefitinib is a cancer medication that interferes with the growth and spread of cancercells in the body. Gefitinib is used to treat non-small cell lung cancer. Gefitinib is sometimes used to treat cancer that has spread to other parts of the body.Indication:
Gefitinib 250mg is a cancer chemotherapy agent. It works by blocking a certain protein (an enzyme called tyrosine kinase). This helps to stop the cancer from growing and spreading.
Gefitinib 250mg tablet is used treating non-small cell lung cancer after other cancer chemotherapy treatments have not been successful. It may also be used for other conditions as determined by your doctor.Mechanism of action:
This leads to inappropriate activation of the anti-apoptotic Ras signalling cascade, eventually leading to uncontrolled cell proliferation. Research on Gefitinib -sensitive non-small cell lung cancers has shown that a mutation in the EGFR tyrosine kinase domain is responsible for activating anti-apoptotic pathways. Gefitinib inhibits EGFR tyrosine kinase by binding to the adenosine triphosphate (ATP)-binding site of the enzyme.Thus the function of the EGFR tyrosine kinase in activating the anti-apoptotic Ras signal transduction cascade is inhibited, and malignant cells are inhibited.Dosage and Administration:
The amount of Gefitinib that you will receive depends on many factors, your general health or other health problems, and the type of cancer or condition being treated.Gefitinib 250mg is a pill, taken by mouth, once daily. It can be taken with or without food.For more Information
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