CIPLA ENTAVIR 0.5 mg, Uses, Side Effects, Price, Composition - India - MHP

Entavir 0.5mg

Introduction:

Entavir is a type of classification of antiviral drug, that fight against HBV reverse transcriptase, which is precisely most related to the active triphosphate form in an intracellular half life of 15 hours. Entavir is a hepatitis B virus nucleoside reverse transcriptase which belongs to class of antiviral drug. 

Mechanism of action:

Entavir is a poor inhibitor of cellular DNA polymerases α,β and  in which mitochondrial DNA polymerase gamma with ki values ranging from 18 to >160µM.

Entecavir combination with natural substance, deoxyguanosine triphosphate functionally prevents all three activities of HBV reverse transcriptase:
Base priming, Ergonomic messenger RNA produce negative strand of reverse transcription, Synthesis of positive strand of HBV DNA.

Prescribed dosage for liver disease

Compensated:In adult dose of Entecavir for chronic HBV is 0.5mg
Decompensated:In adult dose of Entecavir for chronic HBV is 1mg

Uses:

 Its also used on clinical trial data in nucleoside inhibitor treatment for the HBeAg positive and HBeAg negative HBV infection. Entecavir which used to reduce quanity of hepatitis B virus. In adult entavir is used for the treatment of chronic hepatitis B virus infection with the indication of active viral reproduction and either evidence of persistent elevations in serum aminotransferases (ALT OR AST).

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